biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
B3B11, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB1(3688)
Immunogen
source is Jurkat T-leukemic cell line
Application
Immunoprecipitation
Immunohistochemistry on frozen sections
Flow cytometry
Immunoblotting (Western)
Stimulates adhesion of cells to extracellular matrix proteins1
Optimal working dilutions must be determined by end user.
Immunohistochemistry on frozen sections
Flow cytometry
Immunoblotting (Western)
Stimulates adhesion of cells to extracellular matrix proteins1
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Anti-Integrin β1 Antibody, clone B3B11 is an antibody against Integrin β1 for use in FC, IP, WB, FUNC, IH.
Biochem/physiol Actions
Reacts with the human integrin beta1 subunit. Specificity verified by preclearing of beta1in immunoprecipitation, flow cytometry on transfectant cells displaying human beta1 integrin, and reactivity with purified beta1. Epitope lies within the same cluster recognized by MAB2250, and within amino acids 648-670 of the mature beta1 integrin chain.1
Physical form
Format: Purified
Purified immunoglobulin from Protein A Sepharose™ chromatography. Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% sodium azide.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Sarah L Londrigan et al.
Journal of virology, 77(17), 9486-9501 (2003-08-14)
Rotaviruses utilize integrins during virus-cell interactions that lead to infection. Cell binding and infection by simian rotavirus SA11 were inhibited by antibodies (Abs) to the inserted (I) domain of the alpha2 integrin subunit. To determine directly which integrins or other
Interactions between collagen IV and collagen-binding integrins in renal cell repair after sublethal injury.
Nony, P A and Schnellmann, R G
Molecular Pharmacology, 60, 1226-1234 (2001)
Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase.
Satpathy, M; Cao, L; Pincheira, R; Emerson, R; Bigsby, R; Nakshatri, H; Matei, D
Cancer Research null
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB2251 | 04053252357862 |