MAB3291
Anti-HRAS Antibody
CHEMICON®, mouse monoclonal, 7D7.2
别名:
Anti-C-BAS/HAS, Anti-C-H-RAS, Anti-C-HA-RAS1, Anti-CTLO, Anti-H-RASIDX, Anti-HAMSV, Anti-HRAS1, Anti-RASH1, Anti-p21ras
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
7D7.2, monoclonal
Species reactivity:
rat, mouse, human
Application:
ELISA, WB
Citations:
4
产品名称
Anti-H-Ras Antibody, clone 7D7.2, clone 7D7.2, Chemicon®, from mouse
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
7D7.2, monoclonal
species reactivity
rat, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... HRAS(3265)
Immunogen
Full-length recombinant human H-Ras - GST fusion protein
Application
Western blot
ELISA
Optimal working dilutions must be determined by end user.
ELISA
Optimal working dilutions must be determined by end user.
Research Category
Signaling
Signaling
Research Sub Category
MAP Kinases
MAP Kinases
This Anti-H-Ras Antibody, clone 7D7.2 is validated for use in ELISA, WB for the detection of H-Ras.
Biochem/physiol Actions
Recognizes H-Ras (the oncogene of Harvey murine sarcoma virus). Approximate molecular weight of 21 kDa.
Physical form
0.02M phosphate buffer, 0.25M NaCl, pH 7.6, 0.1% sodium azide
Format: Purified
Preparation Note
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.
WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.
WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.
Sasaki, AT; Carracedo, A; Locasale, JW; Anastasiou, D; Takeuchi, K; Kahoud, ER; Haviv et al.
Science Signaling null
Ho-June Lee et al.
Molecular cancer therapeutics, 16(4), 694-704 (2017-02-01)
Cancer cell line profiling to identify previously unrecognized kinase dependencies revealed a novel nonmutational dependency on the DNA damage response checkpoint kinase Chk1. Although Chk1 is a promising therapeutic target in p53-deficient cancers, we found that Ras-MEK signaling engages Chk1
Candida Zuchegna et al.
Redox report : communications in free radical research, 27(1), 150-157 (2022-07-14)
Although the protooncogenes small GTPases Ras are redox-sensitive proteins, how they are regulated by redox signaling in the central nervous system (CNS) is still poorly understood. Alteration in redox-sensitive targets by redox signaling may have myriad effects on Ras stability
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB3291 | 04053252317897 |