MAB3307
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5
clone 41-1E5, Chemicon®, from mouse
别名:
Fibroblast Collagenase, Interstitial Collagenase
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
41-1E5, monoclonal
Application:
ELISA, IHC, WB
Citations:
23
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
41-1E5, monoclonal
species reactivity
rabbit, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... MMP1(4312)
General description
52 kDa
Immunogen
Syntheic peptide aa332-350 of hMMP-1
Epitope: a.a. 332-350 hMMP1
Application
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5 detects level of MMP-1 & has been published & validated for use in ELISA, IH(P) & WB.
Immunoblotting:
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended
ElA
Biochem/physiol Actions
Specifically reacts with precursor and active forms of human MMP-1.
Physical form
Format: Purified
Liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.
Analysis Note
Control
Cervical carcinoma
SKBr-3 cell lysate
Cervical carcinoma
SKBr-3 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1122
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.
Andreea M Bujor,Sashidar Nakerakanti,Erin Morris,Faye N Hant,Maria Trojanowska
Experimental Dermatology null
Immunohistochemical demonstration of collagenase and tissue inhibitor of metalloproteinases (TIMP) in synovial lining cells of rheumatoid synovium
Okada, Y. et al.
Virchows Archiv. B, Cell Pathology Including Molecular Pathology, 59, 305-312 (1990)
Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway.
Deroanne, CF; Hamelryckx, D; Ho, TT; Lambert, CA; Catroux, P; Lapiere, CM; Nusgens, BV
Journal of Cell Science null
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB3307 | 08436037124525 |