Anti-MRP2 Antibody, CT, clone M2 III-6

Bacterial fusion protein of MRP2 containing the 202-aa C-terminal end

Epitope: C-terminus

Detect MRP2 using this Anti-MRP2 Antibody, C-terminus, clone M2 III-6 validated for use in WB, IC, IH, IH(P).

Research Category
Metabolism

Research Sub Category
Toxicology & Drug Resistance

Western blotting: 1:20 - 1:50 with anti-mouse HRP

Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations

Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections; 1:20 on formaldehyde-fixed paraffin-embedded tissues (pretreat with 0.01M citrate, pH 6.0, in dH2O at 100ºC for 5 minutes, repeated 3 times)

Optimal working dilutions must be determined by end user.

This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 over expression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.

Liquid containing 0.7% BSA and 0.1% sodium azide.

Maintain refrigerated at 2-8°C for up to 6 months. For long-term storage store at -20°C.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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