MAB4162
抗-MDR1抗体，细胞外人类特异性Pgp，克隆号MM4.17
clone MM4.17, Chemicon®, from mouse
别名:
P-glycoprotein, CD243, p170, Pgp
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
MM4.17, monoclonal
Species reactivity:
human
Application:
FACS, IHC
Citations:
4
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MM4.17, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunohistochemistry: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
Application
抗-MDR1抗体，细胞外人类特异性Pgp，克隆号MM4.17是一种抗MDR1抗体，用于FC、IH。
流式细胞术
丙酮固定石蜡包埋切片的免疫组化
共聚焦和电子显微镜
ELISA
最佳工作稀释度必须由最终用户进行确定。
丙酮固定石蜡包埋切片的免疫组化
共聚焦和电子显微镜
ELISA
最佳工作稀释度必须由最终用户进行确定。
Biochem/physiol Actions
识别细胞外Pgp结构域的一个表位，并在活（完整）人类MDR细胞中检测低水平的Pgp表达（Cianfriglia，2002）。 使用不同的技术将表位定位到单氨基酸水平（Cianfriglia，1994和Poloni，1995）。
Physical form
形式：纯化
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.
Yasunaga, M; Matsumura, Y
Scientific Reports null
Jingwei Zhang et al.
British journal of pharmacology, 165(1), 120-134 (2011-05-28)
Intracellular pharmacokinetics of anticancer drugs in multi-drug resistance (MDR) cancer cells is hugely important in the evaluation and improvement of drug efficacy. By using adriamycin as a probe drug in MDR cancer cells, we developed a cellular pharmacokinetic-pharmacodynamic (PK-PD) model
Wanyuan Chen et al.
Oncology reports, 41(1), 67-76 (2018-10-27)
Pancreatic cancer (PC) is a lethal solid malignancy with resistance to traditional chemotherapy. Recently, considerable studies have demonstrated the ubiquitous antitumor properties of gene therapy mediated by the oncolytic vaccinia virus. The second mitochondrial‑derived activator of caspase (Smac) has been
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB4162 | 04053252660290 |