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Merck
CN

MAB4315

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
STRO-1, monoclonal
Species reactivity:
human, primate
Application:
FACS, IF
Citations:
27
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biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

STRO-1, monoclonal

species reactivity

human, primate

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunofluorescence: suitable

input

sample type mesenchymal stem cell(s)

isotype

IgM

shipped in

dry ice

target post-translational modification

unmodified

General description

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Immunogen

CD34+ bone marrow cells

Application

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Biochem/physiol Actions

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Analysis Note

Control
Bone marrow cultures

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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实验方案

有关间充质的信息,特别是间充质干细胞培养实验方案用于间充质干细胞(MSC)分离、扩增和分化的分步细胞培养方案。

Information about mesenchyme, specifically mesenchymal stem cell procotols. Step-by-step cell culture protocols for mesenchymal stem cell (MSC) isolation, expansion and differentiation.

商品

Frequently asked questions about mesenchymal stem cells including MSC derivation, expansion, differentiation and allogenic stem cell therapy.

相关内容

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.


Byung Cheol Kim et al.
Journal of biomedical research, 33(2), 122-130 (2019-04-24)
Despite their potential applications in future regenerative medicine, periodontal ligament stem cells (PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining stemness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from
Carol Po Ying Lau et al.
International journal of oncology, 42(2), 437-443 (2012-12-12)
Giant cell tumor of bone (GCT) is a destructive neoplasm of uncertain etiology that affects the epiphyseal ends of long bones in young adults. GCT stromal cells (GCTSCs) are the primary neoplastic cells of this tumor and are the only
Multipotent properties of myofibroblast cells derived from human placenta.
Strakova, Z; Livak, M; Krezalek, M; Ihnatovych, I
Cell and Tissue Research null



全球贸易项目编号

货号GTIN
MAB431504053252579967