MAB4625
Anti-Bcl-X Antibody, clone 2H12
clone 2H12, Chemicon®, from mouse
别名:
Bcl-2-like Protein
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
2H12, monoclonal
Application:
FACS, IF, IHC, IP, WB
Citations:
6
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2H12, monoclonal
species reactivity
rat, pig, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... BCL2L1(598)
General description
Bcl-X has two isoforms, Bcl-XL (long), a 241-aa protein, and Bcl-XS (short), a 178-aa protein lacking a 63 aa domain that is well conserved among members of the Bcl-2 family.
Immunogen
Synthetic peptide, aa 3-14 of human Bcl-X protein. This amino acid sequence is shared by human and murine Bcl-X protein.
Application
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
This Anti-Bcl-X Antibody, clone 2H12 is validated for use in FC, IF, IP, WB, IH for the detection of Bcl-X.
Wstern Blot: 1μg/mL (Hsu, 1997a; Hsu, 1997b)
Flow Cytometry
Immunofluorescence Immunoprecipitation: native protein (2ug/mg protein lysate).
Immunohistochemistry (frozen and paraffin): 2-4ug/mL for 30 minutes at room temperature.
Optimal working dilutions must be determined by end user.
Flow Cytometry
Immunofluorescence Immunoprecipitation: native protein (2ug/mg protein lysate).
Immunohistochemistry (frozen and paraffin): 2-4ug/mL for 30 minutes at room temperature.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
MAB4625 recognizes a protein of 27 kDa, identified as the Bcl-X protein. Reacts with both Bcl-XS and Bcl-XL.
Physical form
Format: Purified
Protein A purified immunoglobulin in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Preparation Note
Maintain at 2-8°C for up to 12 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Anke H Sillars-Hardebol,Beatriz Carvalho,Jeroen Am Belien,Meike de Wit et al.
The Journal of Pathology null
Carles Solà-Riera et al.
PLoS pathogens, 16(2), e1008297-e1008297 (2020-02-08)
Hantaviruses, zoonotic RNA viruses belonging to the order Bunyavirales, cause two severe acute diseases in humans, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantavirus-infected patients show strong cytotoxic lymphocyte responses and hyperinflammation; however, infected cells remain
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB4625 | 04053252666643 |