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Merck
CN

MAB5504

抗-囊泡谷氨酸转运体2抗体

clone 8G9.2, Chemicon®, from mouse

别名:

VGLUT2

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8G9.2, monoclonal
Application:
IHC, WB
Citations:
114
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

8G9.2, monoclonal

species reactivity

mouse, rat

species reactivity (predicted by homology)

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SLC17A6(57084)

General description

囊泡谷氨酸转运蛋白2(VGLUT2)是一种钠依赖性无机磷酸盐共转运蛋白,参与星形胶质细胞释放钙依赖性谷氨酸。它在表现出经典兴奋性特征的突触中仅在位于突触小泡的神经元子集中表达。在缺乏VGLUT1的大脑区域中发现了VGLUT2 mRNA,VGLUT1是一种相关蛋白,也显示出钠依赖性无机磷酸盐共转运蛋白活性。
56 kDa

Application

使用经验证可用于WB、IH的抗囊泡谷氨酸转运蛋白2抗体检测囊泡谷氨酸转运蛋白2。
免疫组织化学: 一个先前批次以1:50-1:300稀释度在浮动小鼠脑切片上使用ABC和NiDAB起作用。

最佳工作稀释度必须由最终用户确定。

Biochem/physiol Actions

与VGLUT2(囊泡谷氨酸转运蛋白2)反应。

Physical form

小鼠单克隆抗体,溶于含0.1%叠氮化钠的PBS中。
形式:纯化

Analysis Note

通过蛋白质印迹法对小鼠脑裂解物进行评价。

蛋白质印迹分析: 该抗体以1:500稀释度在10 µg小鼠脑裂解物中检测到VGLUT2。

Other Notes

浓度:关于批次特定浓度请参见检验报告。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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存储类别

10 - Combustible liquids

wgk

WGK 2



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商品

Human iPSC neural differentiation media and protocols used to generate neural stem cells, neurons and glial cell types.


B Fyk-Kolodziej et al.
Neuroscience, 178, 218-239 (2011-01-08)
An immunocytochemical comparison of vGluT1 and vGluT3 in the cochlear nucleus (CN) of deafened versus normal hearing rats showed the first example of vGluT3 immunostaining in the dorsal and ventral CN and revealed temporal and spatial changes in vGluT1 localization
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
Duvick, L; Barnes, J; Ebner, B; Agrawal, S; Andresen, M; Lim, J; Giesler, GJ; Zoghbi, HY; Orr, HT
Neuron null
Y Cai et al.
Neuroscience, 215, 160-173 (2012-05-01)
The glomeruli are the first synaptic relay on the olfactory pathway and play a basic role in smell perception. Glomerular degeneration occurs in humans with age and in Alzheimer's disease (AD). The glomeruli heavily express β-amyloid precursor protein (APP), β-secretase



全球贸易项目编号

货号GTIN
MAB550404053252397523