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Merck
CN

MABD24A4

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate

clone 7F7.1, from mouse, ALEXA FLUOR 488

别名:

Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR 488
Clone:
7F7.1, monoclonal
Application:
ICC
Citations:
4
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biological source

mouse

Quality Level

conjugate

ALEXA FLUOR 488

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

7F7.1, monoclonal

species reactivity

human

technique(s)

immunocytochemistry: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NANOG(79923)

General description

The uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDa
NANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.

Application

Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.

Physical form

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Analysis Note

Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Quan Qi et al.
International journal of molecular medicine, 35(3), 569-578 (2014-12-20)
The present study aimed to investigate the X chromosome inactivation (XCI) status in long-term cultured human parthenogenetic embryonic stem cells. One human embryonic stem (hES) cell line and 2 human parthenogenetic embryonic stem (hPES) cell lines were subjected to long-term
Vanessa Sauer et al.
Cell transplantation, 25(12), 2221-2243 (2016-08-12)
Although several types of somatic cells have been reprogrammed into induced pluripotent stem cells (iPSCs) and then differentiated to hepatocyte-like cells (iHeps), the method for generating such cells from renal tubular epithelial cells shed in human urine and transplanting them
Daniel Rodrigo Marinowic et al.
Molecular medicine reports, 15(4), 2049-2056 (2017-03-06)
Focal cortical dysplasia (FCD) is caused by numerous alterations, which can be divided into abnormalities of the cortical architecture and cytological variations; however, the exact etiology of FCD remains unknown. The generation of induced pluripotent stem cells (iPSCs) from the



全球贸易项目编号

货号GTIN
MABD24A404053252695117