Anti-α-Synuclein (SNCA) Antibody

14.46 kDa calculated

Recombinant human alpha-synuclein oxidized/nitrated in vitro with peroxynitrite.

ELISA Analysis: A representative lot detected alpha synuclein in ELISA applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).

Immunohistochemistry (Paraffin) Analysis: A representative lot detected alpha synuclein in Immunohistochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46; Sorrentino, Z.A., et. al. (2017). Mol Neurodegener. 12(1):40; Peng, C., et. al. (2018). Nature. 557(7706):558-563).

Western Blotting Analysis: A representative lot detected alpha synuclein in Western Blotting applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).

Immunocytochemistry Analysis: A representative lot detected alpha synuclein in Immunocytochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).

Clone Syn506 is a mouse monoclonal antibody that detects misfolded alpha-synuclein. It targets an epitope within 20 amino acids from the N-terminal region.

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Immunohistochemistry (Paraffin) in human Parkinson′s diseased brain tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected alpha synuclein in human Parkinson′s diseased brain tissue sections.

Human, Mouse.

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