MABN92-AF647
Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor™ 647 Conjugate
clone 20A12.1, from mouse, ALEXA FLUOR™ 647
别名:
Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.45
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR™ 647
Clone:
20A12.1, monoclonal
Application:
IF
Citations:
2
biological source
mouse
Quality Level
conjugate
ALEXA FLUOR™ 647
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
20A12.1, monoclonal
species reactivity
mouse, human, rat
technique(s)
immunofluorescence: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... AIF1(199)
General description
~17 kDa observed.
Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.
Application
Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor™ 647 Conjugate is an antibody against AIF1 for use in Immunofluorescence.
The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.
Analysis Note
Evaluated by Immunofluorescence in human spleen tissue.
Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Immunofluorescence Analysis: A 1:50 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Other Notes
Concentration: Please refer to lot specific datasheet.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Fumio Takahashi et al.
iScience, 25(5), 104278-104278 (2022-05-17)
Neurodegeneration is a process involving both cell autonomous and non-cell autonomous neuron loss, followed by a collapse of neural networks, but its pathogenesis is poorly understood. We have previously demonstrated that Eomes-positive helper T (Eomes + Th) cells recognizing LINE-1(L1)-derived prototypic
Pei Song et al.
Journal of healthcare engineering, 2021, 3048383-3048383 (2021-10-12)
Cardiopulmonary bypass (CPB) is mainly used during cardiac surgeries that treat ischemic, valvular, or congenital heart disease and aortic dissections. The disorders of central nervous system (CNS) that occur after cardiopulmonary bypass are attracting considerable interest. Postoperative neurocognitive disorders (PND)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MABN92-AF647 | 04055977335262 |