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Merck
CN

00990

乙酰氯

≥99.0% (T), liquid, puriss. p.a.

别名:

Acetic acid chloride, Acetic chloride, Ethanoyl chloride

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关于此项目

线性分子式:
CH3COCl
化学文摘社编号:
分子量:
78.50
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39050501
UNSPSC Code:
12352100
EC Number:
200-865-6
MDL number:
Beilstein/REAXYS Number:
605303
Assay:
≥99.0% (T)
Form:
liquid
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产品名称

乙酰氯, puriss. p.a., ≥99.0% (T)

vapor density

2.7 (vs air)

Quality Level

vapor pressure

11.69 psi ( 20 °C), 32.33 psi ( 55 °C)

grade

puriss. p.a.

assay

≥99.0% (T)

form

liquid

autoignition temp.

1353 °F

expl. lim.

19 %

refractive index

n20/D 1.389

bp

52 °C (lit.)

mp

−112 °C (lit.)

density

1.104 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.1 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.5 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.1 mg/kg, Na: ≤0.5 mg/kg, Ni: ≤0.02 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

functional group

acyl chloride

SMILES string

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

InChI key

WETWJCDKMRHUPV-UHFFFAOYSA-N

General description

乙酰氯(酰氯)是用于酯化和Friedel-Crafts酰化反应的乙酰化试剂。

Application

乙酰氯可以用作:
  • 色谱-质谱联用(MS)降解聚氧乙二醇单烷基醚,测定乙氧基化程度的降解剂。
  • 用于羧酸酯化、N-boc脱保护和磷酰胺溶剂分解反应的含醇试剂。


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pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

41.0 °F - closed cup

flash_point_c

5 °C - closed cup

ppe

Faceshields, Gloves, Goggles

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lillington JM, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 111(1), 91-98 (1981)
Comparisons of O-acylation and Friedel-Crafts acylation of phenols and acyl chlorides and Fries rearrangement of phenyl esters in trifluoromethanesulfonic acid: Effective synthesis of optically active homotyrosines
Murashige R, et al.
Tetrahedron, 67(3), 641-649 (2011)
Uta Ceglarek et al.
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335614-50G04061831829433
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