07260
6-氨基己酸
≥98.5% (NT)
别名:
6-氨基己酸, 6-ACA, Aca, Acp, Aha, Ahx, 氨基己酸, ε-氨基己酸, EACA
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关于此项目
线性分子式:
H2N(CH2)5CO2H
化学文摘社编号:
分子量:
131.17
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-469-3
Beilstein/REAXYS Number:
906872
MDL number:
Quality Level
assay
≥98.5% (NT)
mp
207-209 °C (dec.) (lit.)
SMILES string
NCCCCCC(O)=O
InChI
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key
SLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Information
human ... PLAT(5327), PLG(5340)
General description
6-氨基己酸是丝氨酸蛋白酶抑制剂。它与天然氨基酸赖氨酸在结构上相似，但少一个α-氨基。
Application
6-氨基己酸被用作间充质干细胞肌腱分化用生长培养基的组分。它还用于制备改性石墨烯量子点。
Biochem/physiol Actions
赖氨酸类似物。促进纤溶酶的快速解离，从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。
赖氨酸类似物。促进纤溶酶的快速解离，从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。据报道可抑制纤溶酶原与活化的血小板结合。 早期报告表明，它抑制补体系统第一成分的激活。结合羧肽酶 B并使其灭活。
Other Notes
改善膜蛋白在电泳中的溶解
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
404.6 - 408.2 °F
flash_point_c
207 - 209 °C
ppe
dust mask type N95 (US), Eyeshields, Gloves
H Schägger et al.
Analytical biochemistry, 199(2), 223-231 (1991-12-01)
A discontinuous electrophoretic system for the isolation of membrane proteins from acrylamide gels has been developed using equipment for sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Coomassie dyes were introduced to induce a charge shift on the proteins and aminocaproic acid
Lajos Gera et al.
Peptides, 34(2), 433-446 (2012-02-22)
Peptide agonists and antagonists of both bradykinin (BK) B(1) and B(2) receptors (B(1)R, B(2)R) are known to tolerate to a certain level N-terminal sequence extensions. Using this strategy, we produced and characterized the full set of fluorescent ligands by extending
Ai Kia Yip et al.
Biophysical journal, 104(1), 19-29 (2013-01-22)
Cells sense the rigidity of their substrate; however, little is known about the physical variables that determine their response to this rigidity. Here, we report traction stress measurements carried out using fibroblasts on polyacrylamide gels with Young's moduli ranging from
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