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Merck
CN

12279

1,2-丙二醇

analytical standard

别名:

1,2-PDO, 丙二醇

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关于此项目

线性分子式:
CH3CH(OH)CH2OH
化学文摘社编号:
分子量:
76.09
NACRES:
NA.24
E Number:
E490
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-338-0
MDL number:
Beilstein/REAXYS Number:
1340498
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grade

analytical standard

Quality Level

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.7% (GC)

autoignition temp.

779 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

12.5 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.432 (lit.), n20/D 1.433

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

General description

1,2-丙二醇是一种化学性质类似于乙二醇的化合物,广泛用于汽车防冻剂、活性炭制剂、化妆品、饮料、软膏等。它可用作水溶性差的药物静脉注射制剂的稀释剂。
这种物质被列入EU第10/2011号法规中用于与食品接触的塑料的正面清单。

请点击此处查看列入10/2011 的所有化合物的参考物质。

Application

在通过气相色谱-质谱法检测蜂蜜、蜜蜂和花粉中的环境污染物时,1,2-丙二醇可用作分析物保护剂。使用顶空气相色谱(HS-GC)技术,它也可用作定量分析生物流体中分析物的分析参考标准品。
有关理想仪器技术的更多信息,参见产品#8242;s分析证书。想要获得更多支持,请联系技术服务部。


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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

217.4 °F - closed cup

flash_point_c

103 °C - closed cup

ppe

Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

99%;甘油,≥99.5%;四甘醇,99%


R S Rajasenan et al.
Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)
Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was
G A Reichard et al.
Diabetes, 35(6), 668-674 (1986-06-01)
Plasma acetone turnover rates were measured with the primed continuous infusion of 2-[14C]acetone in patients with moderate to severe diabetic ketoacidosis. Plasma acetone turnover rates ranged from 1.52 to 15.9 mumol X kg-1 X min-1 (108-1038 mumol X 1.73 m-2
H K Vaddi et al.
Journal of pharmaceutical sciences, 91(7), 1639-1651 (2002-07-13)
The respective alcoholic terpenes carvacrol, linalool, and alpha-terpineol were used at 5% w/v in propylene glycol (PG) to increase the in vitro permeation of haloperidol (HP) through human skin. The possible enhancement mechanism was then elucidated with HP-stratum corneum (SC)



全球贸易项目编号

货号GTIN
12279-1ML-F04061838721778
12279-5ML-F04061838721785