Quality Level
assay
≥99.0% (N), ≥99.0%
form
powder
quality
for spectrophotometric det. of Cu
technique(s)
UV/Vis spectroscopy: suitable
mp
210-214 °C
SMILES string
O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2
InChI
1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
InChI key
DSRJIHMZAQEUJV-UHFFFAOYSA-N
General description
Cuprizone[双(环己酮)恶二氢腙]是一种物理上不稳定的化合物,是一种公认的神经毒性剂。
Application
为了研究胼胝体中髓鞘再生的病理生物学,使用Cuprizone[双(环己酮)恶二氢腙]在中枢神经系统中进行毒性脱髓鞘,以研究人类脱髓鞘疾病,如多发性硬化症。 它还可用于研究神经炎症的组成部分。
Other Notes
用于 Cu(II) 的分光光度测定
当存在铜盐时,该配体可以在温水中催化 Ullmann 类 C-N 键合成反应。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
R.K. Rohde
Analytical Chemistry, 38, 911-911 (1966)
Cortical demyelination is prominent in the murine cuprizone model and is strain-dependent.
Thomas S
The American Journal of Pathology, 174 (4), 1053-1061 (2008)
The protective role of nitric oxide in a neurotoxicant-induced demyelinating model.
Arnett H
Journal of Immunology, 168 (1), 427-433 (2002)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 91315-25G | 04061836828158 |
| 14690-100G | 04061838737168 |
| 14690-25G | 04061838737175 |