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Merck
CN

235989

Brij® L4聚氧乙烯月桂醚

average Mn ~362

别名:

四聚乙二醇单月桂醚, 聚氧乙烯 (4) 月桂醚

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关于此项目

线性分子式:
(C20H42O5)n
化学文摘社编号:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
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description

non-ionic

Quality Level

form

solid or liquid

mol wt

average Mn ~362

impurities

≤1% Water

refractive index

n20/D 1.451 (lit.)

mp

48 °C

solubility

water: insoluble

density

0.95 g/mL at 25 °C (lit.)

HLB

9

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

InChI key

WPMWEFXCIYCJSA-UHFFFAOYSA-N

General description

Brij® L4 是一种非离子表面活性剂。它含有一个连接氧乙烯基头基的烷基(C12)尾。

Application

Brij® L4 已被用于:
  • 作为表面活性剂采用微乳液技术合成氧化铜(I)(Cu2O) 球形纳米颗粒
  • 作为非离子表面活性剂用于制备反胶束以合成Pt3Co 合金纳米颗粒
  • 作为表面活性剂用于改善疏水材料界面偶联的效率并生成水凝胶

Biochem/physiol Actions

Brij® L4 具有两亲性。Brij L4 含有疏水和亲水区域,可以形成胶束并使疏水药物分散进入胶束核中。这相应地改善了药物的溶解性。Brij L4也对乳腺癌耐药蛋白(BCRP)介导的药物外排有强烈的抑制作用。与其它常用表面活性剂相比,它对Taq吸附的抑制作用更强。Brij L4 有助于在标准Taq浓度下进行皮升反应体积的液滴聚合酶链式反应(PCR)。

Legal Information

Brij is a registered trademark of Croda International PLC


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signalword

Warning

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Darío Morais et al.
Rhinology, 50(1), 80-86 (2012-04-04)
Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the
N Shadid et al.
The British journal of surgery, 99(8), 1062-1070 (2012-05-26)
New minimally invasive treatment modalities, such as ultrasound-guided foam sclerotherapy (UGFS), are becoming more popular. In a multicentre randomized controlled non-inferiority trial, the effectiveness and costs of UGFS and surgery for treatment of the incompetent great saphenous vein (GSV) were
B McAree et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 43(6), 721-725 (2012-04-18)
To compare the half-life of STD and polidocanol air-based foams and the damage they inflict upon human great saphenous vein in an in-vitro model. The time for the volume of 3% STD and polidocanol foams to reduce by 10% (T(90))



全球贸易项目编号

货号GTIN
235989-100ML04061838785398
235989-1L04061838785404
235989-250ML04061838785411
235989-5ML04061837595141