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Merck
CN

33975

卡洛芬

VETRANAL®, analytical standard

别名:

6-氯-α-甲基-9 H -咔唑-2-乙酸

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关于此项目

经验公式(希尔记法):
C15H12ClNO2
化学文摘社编号:
分子量:
273.71
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
258-712-4
MDL number:
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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChI key

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

General description

卡洛芬是一种非甾体抗炎药,通常用于治疗动物退行性关节病,如犬骨关节炎等。它也可以像止痛剂一样用于控制猫卵巢子宫切除术期间产生的术后疼痛。

Application

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Angelo D Favia et al.
Journal of medicinal chemistry, 55(20), 8807-8826 (2012-10-10)
Pain and inflammation are major therapeutic areas for drug discovery. Current drugs for these pathologies have limited efficacy, however, and often cause a number of unwanted side effects. In the present study, we identify the nonsteroidal anti-inflammatory drug carprofen as
Laura Bertolacci et al.
Journal of the American Chemical Society, 135(1), 22-25 (2012-12-18)
In addition to inhibiting the cyclooxygenase (COX)-mediated biosynthesis of prostanoids, various widely used nonsteroidal anti-inflammatory drugs (NSAIDs) enhance endocannabinoid signaling by blocking the anandamide-degrading membrane enzyme fatty acid amide hydrolase (FAAH). The X-ray structure of FAAH in complex with the
I N Plessas et al.
The Veterinary record, 171(20), 501-501 (2012-10-27)
The disease complex Chiari-like malformation (CM) and syringomyelia (SM) has been associated with the development of neuropathic pain (NeP), and commonly affects Cavalier King Charles spaniels (CKCS). This prospective cohort study followed 48 CKCSs with CM and/or SM and clinical



全球贸易项目编号

货号GTIN
33975-100MG-R04061826752555