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46161

地美环素 盐酸盐 水合物

VETRANAL®, analytical standard

别名:

去甲基金霉素 盐酸盐

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关于此项目

经验公式（希尔记法）:
C21H21ClN2O8 · HCl · xH2O
化学文摘社编号:
64-73-3
分子量:
501.31 (anhydrous basis)
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757091
EC Number:
200-592-2
Beilstein/REAXYS Number:
5705221
MDL number:
MFCD00149217
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grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

O.Cl.CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O

InChI

1S/C21H21ClN2O8.ClH.H2O/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31);1H;1H2/t6-,7-,14-,15-,21-;;/m0../s1

InChI key

LZJOUJFCRCXBBC-XZJYMHMKSA-N

General description

Chemical structure: tetracycline

Application

Demeclocycline hydrochloride hydrate may be used as an internal standard for the determination of:
  • Oxytetracycline and tetracycline in pig manure samples by ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometer equipped with electrospray ionization source (QqQ-ESI-MS/MS) and dynamic multiple reaction monitoring (dMRM) mode of detection.
  • Oxytetracycline hydrochloride in dairy products by UHPLC-QqQ-ESI-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCC8240
BCBX9925

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Development and Validation of a Multi-class UHPLC-MS/MS Method for Determination of Antibiotic Residues in Dairy Products
Schwaiger B, et al.
Food Analytical Methods, 14, 1417-1434 (2018)
J Bousek et al.
Journal of environmental management, 223, 545-553 (2018-07-01)
The fate of four widely used veterinary antibiotics (doxycycline, flumequine, oxytetracycline and tetracycline) during manure upcycling was investigated at laboratory and pilot scale. The pilot was operated continuously, while the laboratory scale in batch mode. Both set-ups consisted of anaerobic
Guy Decaux
Annales d'endocrinologie, 73(2), 130-134 (2012-04-28)
The vaptans are non-peptide arginine-vasopressin-receptor antagonists, that are orally and intravenously active. A few vaptans have undergone sufficient clinical development to be on the market. In the EU only tolvaptan is accepted to treat hyponatremia related to SIADH. The place
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货号GTIN
46161-100MG04061832344607