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Merck
CN

52517

1,1,1,3,3,3-六氟-2-丙醇

derivatization grade (GC derivatization), LiChropur, ≥99.8%

别名:

HFP, 六氟异丙醇

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关于此项目

线性分子式:
(CF3)2CHOH
化学文摘社编号:
分子量:
168.04
UNSPSC Code:
12352104
NACRES:
NA.05
PubChem Substance ID:
EC Number:
213-059-4
Beilstein/REAXYS Number:
1841007
MDL number:
Assay:
≥99.8% (GC), ≥99.8%
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grade

derivatization grade (GC derivatization)

Quality Level

assay

≥99.8% (GC), ≥99.8%

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations, reagent type: derivatization reagent
reaction type: Esterifications

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.275 (lit.)

bp

59 °C (lit.)

mp

−4 °C (lit.)

density

1.596 g/mL at 25 °C (lit.)

SMILES string

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChI key

BYEAHWXPCBROCE-UHFFFAOYSA-N

General description

六氟异丙醇(HFP)通常用于天然状态蛋白质变性,还能稳定未折叠多肽和蛋白质,如β-乳球蛋白和蜂毒素的a-螺旋构型。

Application

适于衍生化谷氨酸、高香草酸、异香草醛和二羟基苯乙酸和Υ-氨基丁酸。

Other Notes

1,1,1,3,3,3-六氟-2-丙醇中的尺寸排阻色谱
六氟异丙基酯、N-五氟丙基和三氟乙酰基的衍生化试剂。

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Faceshields, Gloves, Goggles



历史批次信息供参考:

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Cooperative a-helix formation of ?-lactoglobulin and melittin induced by hexafluoroisopropanol
Hirota, Nami, Yuji Goto, and Kazuko Mizuno.
Protein Science, 6 (2), 416-421 (1997)
Thomas H Mourey et al.
Journal of chromatography. A, 964(1-2), 169-178 (2002-08-30)
1,1,1,3,3,3-Hexafluoroisopropanol is re-examined as an eluent for size-exclusion chromatography (SEC) of polyesters, nylons, and other polar polymers. It is shown that anomalous SEC behavior reported in previous literature can be eliminated by adding 0.01 M tetraethylammonium nitrate to the eluent.
Dave W Chen et al.
International journal of pharmaceutics, 430(1-2), 335-341 (2012-04-24)
This study investigated the in vitro release of vancomycin, gentamicin, and lidocaine from novel electrospun sandwich-structured polylactide-polyglycolide (PLGA)/collagen nanofibrous membranes. For the electrospinning of biodegradable membranes, PLGA/collagen and PLGA/vancomycin/gentamicin/lidocaine were separately dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP). They were then electrospun into



全球贸易项目编号

货号GTIN
134708-100G04061835517794
134708-25G04061835554201
32053-250MG04061826701966
52517-10ML04061832550411
52517-1ML-KC04061838082978
52517-10X1ML04061838082961
52517-50ML04061832550428