59964
组胺
analytical standard
别名:
2-(4-咪唑基)乙胺
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关于此项目
经验公式（希尔记法）:
C5H9N3
化学文摘社编号:
分子量:
111.15
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-100-6
Beilstein/REAXYS Number:
2012
MDL number:
grade
analytical standard
Quality Level
assay
≥97.0% (TLC), ≥97.0% (anhydrous basis, NT)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤4.0% water
color
white to light yellow
bp
167 °C/0.8 mmHg (lit.)
mp
83-84 °C (lit.)
format
neat
storage temp.
−20°C
SMILES string
NCCc1c[nH]cn1
InChI
1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI key
NTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
Application
有关理想仪器技术的更多信息，参见产品#8242;s分析证书。想要获得更多支持，请联系技术服务部。
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可以使 Ca2+ 移动；H2 的活化可促进神经元中腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。
内源性 H1 和 H2 组胺受体激动剂；可活化一氧化氮合成酶；有效的血管舒张剂。
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Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
Mohamed H Shamji et al.
The Journal of allergy and clinical immunology, 135(4), 913-921 (2014-12-03)
Immunotherapy inhibits basophil histamine release, but the assay is cumbersome, and no one has studied the effects of immunotherapy withdrawal. Intracellular fluorochrome-labeled diamine oxidase (DAO) was used as a novel functional readout of basophil histamine release after immunotherapy. Results were
Andrea Strasser et al.
Trends in pharmacological sciences, 34(1), 13-32 (2012-12-12)
Histamine is a biogenic amine that exerts its biological effects as a neurotransmitter and local mediator via four histamine receptor (HR) subtypes (H(x)Rs) - H(1)R, H(2)R, H(3)R, and H(4)R - belonging to the superfamily of G-protein-coupled receptors (GPCRs). All four
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 59964-100MG | 04061832644769 |