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85615

鞘髓磷脂

Name: 鞘髓磷脂
Brand: SIAL

from chicken egg yolk, ≥98.0% (TLC)

别名:

N-Acyl-4-sphingenyl-1-O-phosphorylcholine, N-酰基-D-鞘氨醇-1-磷酸胆碱

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关于此项目

化学文摘社编号:

85187-10-6

UNSPSC Code:

12352211

NACRES:

NA.25

EC Number:

286-097-2

MDL number:

MFCD00132361

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属性

biological source

chicken egg yolk

Quality Level

100

assay

≥98.0% (TLC)

form

powder

functional group

phospholipid

lipid type

sphingolipids

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@H]([C@@H](NC=O)COP(O)(OCC[N+](C)(C)C)=O)O

InChI

1S/C24H49N2O6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(28)23(25-22-27)21-32-33(29,30)31-20-19-26(2,3)4/h17-18,22-24,28H,5-16,19-21H2,1-4H3,(H-,25,27,29,30)/p+1/b18-17+/t23-,24+/m0/s1

InChI key

LRYZPFWEZHSTHD-HEFFAWAOSA-O

说明

Application

舌苔的非靶向脂质组学分析揭示了结肠直肠癌的独特脂质特性。: 该研究证明了通过非侵入性方法来识别结直肠癌癌症生物标志物的鞘磷脂分析的创新用途。该研究强调了脂质组学在癌症诊断中的潜力，重点介绍了鞘磷脂在个性化药物策略开发中的关键作用（Chen Q et al., 2024）。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

LC/MS Analysis of Phospholipids in Milk on Asc

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

Pellet-free isolation of human and bovine milk extracellular vesicles by size-exclusion chromatography.

Kristine Blans et al.

Journal of extracellular vesicles, 6(1), 1294340-1294340 (2017-04-08)

Studies have suggested that nanoscale extracellular vesicles (EV) in human and bovine milk carry immune modulatory properties which could provide beneficial health effects to infants. In order to assess the possible health effects of milk EV, it is essential to

S. aureus alpha-toxin monomer binding and heptamer formation in host cell membranes - Do they determine sensitivity of airway epithelial cells toward the toxin?

Nils Möller et al.

PloS one, 15(5), e0233854-e0233854 (2020-05-30)

Alpha-toxin (Hla) is a major virulence factor of Staphylococcus aureus (S. aureus) and plays an important role in S. aureus-induced pneumonia. It binds as a monomer to the cell surface of eukaryotic host cells and forms heptameric transmembrane pores. Sensitivities

全球贸易项目编号

货号	GTIN
85615-250MG	04061833608012
85615-1G	04061826752098
85615-50MG	04061833026878