90527
硫酸羟氯喹
analytical standard
别名:
7-氯-4-[4-（N-乙基-N-b-羟乙基氨基）-1-甲基丁氨基] 喹啉硫酸盐
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关于此项目
经验公式（希尔记法）:
C18H26ClN3O · H2SO4
化学文摘社编号:
分子量:
433.95
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
212-019-3
MDL number:
grade
analytical standard
Quality Level
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
packaging
pkg of 50 mg
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤1.0% water
color
white to off-white
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChI key
JCBIVZZPXRZKTI-UHFFFAOYSA-N
Gene Information
human ... TLR7(51284), TLR9(54106)
General description
硫酸羟氯喹（Hydroxychloroquine Sulphate）是羟氯喹（HCQ，赛能）的盐，它是一种4-氨基喹啉类抗病毒药物。
Application
硫酸羟氯喹可用作分析标准品，用于通过各种分析技术测定药物制剂 和生物样品 中的分析物。
Biochem/physiol Actions
硫酸羟氯喹是一种抗炎（通过肿瘤坏死因子）、疾病调节抗风湿药物（DMARD）和血红素聚合酶抑制剂。
硫酸羟氯喹是一种抗炎（通过肿瘤坏死因子）、疾病调节抗风湿药物（DMARD）和血红素聚合酶抑制剂。 它可用于治疗疟疾。
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hcodes
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysis of blood and urine samples for hydroxychloroquine and three major metabolites by high-performance liquid chromatography with fluorescence detection
Williams SB, et al.
Journal of Chromatography. B, Biomedical Applications, 433(11), 197-206 (1988)
High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma
Brown RR, et al.
Journal of Chromatography. B, Biomedical Applications, 377(11), 454-459 (1986)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Charlier B,et al.
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 90527-50MG | 04061833247044 |