97622
2-巯基乙醇
derivatization grade (HPLC), LiChropur™, ≥99.0% (GC)
别名:
β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
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关于此项目
线性分子式:
HSCH2CH2OH
化学文摘社编号:
分子量:
78.13
UNSPSC Code:
23151817
NACRES:
NA.05
PubChem Substance ID:
EC Number:
200-464-6
Beilstein/REAXYS Number:
773648
MDL number:
grade
derivatization grade (HPLC)
Quality Level
vapor density
2.69 (vs air)
vapor pressure
1 mmHg ( 20 °C)
assay
≥99.0% (GC)
form
liquid
quality
LiChropur™
expl. lim.
18 %
concentration
14.3 M (pure liquid)
technique(s)
HPLC: suitable
refractive index
n20/D 1.500 (lit.), n20/D 1.500-1.502
bp
157 °C (lit.)
density
1.114 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
OCCS
InChI
1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
InChI key
DGVVWUTYPXICAM-UHFFFAOYSA-N
General description
2-巯基乙醇是一种硫醇化合物，在体外对小鼠淋巴瘤L1210细胞显示出生长促进作用。它还能增强淋巴细胞培养物的活性、胚细胞转化和抗体形成。
Application
BME 适用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键，通常用于 SDS-PAGE 的样品缓冲液，浓度为 5%。切割分子间（亚基之间）二硫键允许蛋白质的亚基在 SDS-PAGE 上独立分离。切割分子内（亚基内）二硫键可使亚基完全变性，从而使每个肽根据其链长迁移，而不受二级结构的影响。
适用于胺基团的衍生化
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
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Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
target_organs
Liver,Heart
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
法规信息
危险化学品
此项目有
Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro. Role of the mixed disulfide of 2-mercaptoethanol and cysteine
Ishii T, et al.
The Journal of Biological Chemistry, 256(23), 12387-12392 (1981)
Leon Tribolet et al.
The Journal of infectious diseases, 211(3), 416-425 (2014-08-21)
Na-ASP-2 is an efficacious hookworm vaccine antigen. However, despite elucidation of its crystal structure and studies addressing its immunobiology, the function of Na-ASP-2 has remained elusive. We probed a 9000-protein human proteome microarray with Na-ASP-2 and showed binding to CD79A
Katharina Rothe et al.
Blood, 123(23), 3622-3634 (2014-04-24)
Previous studies demonstrated that imatinib mesylate (IM) induces autophagy in chronic myeloid leukemia (CML) and that this process is critical to cell survival upon therapy. However, it is not known if the autophagic process differs at basal levels between CML
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 97622-10X1ML | 04061833325087 |
| 97622-1ML-KC | 04061838089250 |
| 97622-10ML | 04061833325070 |
| 97622-1ML | 04061838202598 |