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Merck
CN

A0363000

盐酸金刚烷胺 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

1-氨基金刚烷 盐酸盐, 1-金刚烷胺 盐酸盐, NSC 83653, 三环[3.3.1.1 3,7 ] 癸烷-1-胺 盐酸盐

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关于此项目

经验公式(希尔记法):
C10H17N · HCl
化学文摘社编号:
分子量:
187.71
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4198854
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grade

pharmaceutical primary standard

API family

amantadine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H][C@@]12C[C@@]3([H])C[C@@]([H])(C1)CC(N)(C2)C3

InChI

1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H/t7-,8+,9-,10-;

InChI key

WOLHOYHSEKDWQH-SOVZANNPSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Amantadine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

多巴胺释放剂用于治疗帕金森综合征和药物引起的锥体外系反应。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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flash_point_f

Not applicable

flash_point_c

Not applicable

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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F Y Aoki et al.
Clinical pharmacokinetics, 14(1), 35-51 (1988-01-01)
Amantadine is a drug with diverse uses ranging from prevention of influenza A illness to the treatment of patients with Parkinson's disease. It is available only in oral formulations from which it is well absorbed and widely distributed, little drug
Amantadine hydrochloride: current and new uses.
S de Roin et al.
The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 22(5), 322-325 (1990-10-01)
R L Tominack et al.
Infectious disease clinics of North America, 1(2), 459-478 (1987-06-01)
Amantadine and rimantadine are oral antiviral drugs useful in the prophylaxis and treatment of influenza A virus infections. This article reviews the pharmacology, antiviral activity and mechanism of action, pharmacokinetics, toxicities, efficacy, and clinical applications of these agents. When administered



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货号GTIN
A036300004061833327814