A4673
阿苯达唑
analytical standard, ≥98%
别名:
5-(丙硫基)-2-苯并咪唑氨基甲酸甲酯
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关于此项目
经验公式（希尔记法）:
C12H15N3O2S
化学文摘社编号:
分子量:
265.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
259-414-7
MDL number:
grade
analytical standard
Quality Level
assay
≥98%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
InChI
1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI key
HXHWSAZORRCQMX-UHFFFAOYSA-N
General description
阿苯达唑是可用于治疗人胃肠道蠕虫病的苯并咪唑衍生物。它抑制微管，并阻断葡萄糖摄取，导致糖原储备的耗尽，并降低易感寄生虫幼虫和成虫阶段的三磷酸腺苷（ATP）的形成。
化学结构：苯并咪唑
Application
阿苯达唑可用作小鼠血浆中高效液相色谱法（HPLC）测定阿苯达唑及其主要代谢物（阿苯达唑亚砜和阿苯达唑砜）的参考标准。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
结合微管蛋白并抑制微管的聚合。
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
target_organs
Adrenal gland,Blood,male reproductive organs,spleen
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
农药列管产品
此项目有
Role of excipients in the crystallization of Albendazole.
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Castro L S E P W, et al.
Redox Biology, 10, 90-99 (2016)
Martin Spicher et al.
Antimicrobial agents and chemotherapy, 52(9), 3447-3450 (2008-07-16)
In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A4673-10G | 04061833374887 |