A8097
吖啶橙 盐酸盐 溶液
>95.0% purity (HPLC), solution
别名:
3,6-双（二甲氨基）吖啶 盐酸盐
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关于此项目
经验公式（希尔记法）:
C17H19N3 · HCl
化学文摘社编号:
分子量:
301.81
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
3575587
产品名称
吖啶橙 盐酸盐 溶液, 10 mg/mL in H2O, ≥95.0% (HPLC)
Quality Level
assay
≥95.0% (HPLC)
form
solution
concentration
10 mg/mL in H2O
technique(s)
microbe id | staining: suitable
color
orange to red
εmax
47-54 at 486-492 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cl[H].CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C
InChI
1S/C17H19N3.ClH/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;/h5-11H,1-4H3;1H
InChI key
VSTHNGLPHBTRMB-UHFFFAOYSA-N
Application
吖啶橙盐酸盐溶液已用于研究自噬性细胞死亡。也用于染色体的染色。
Biochem/physiol Actions
吖啶橙 (Acridine Orange) 是一种异染性染料，可以染色 DNA、RNA 和酸性糖胺聚糖。低浓度时嵌入 DNA 并沉淀 RNA。然而，在高浓度时，它使 RNA 和 DNA 变性并沉淀。吖啶橙也用于分析自噬。以 pH 依赖性方式进入酸性细胞器。在中性 pH 条件下，吖啶橙发出绿色荧光，在酸性条件下，吖啶橙在酸性细胞器中聚集，发出鲜红色荧光。
signalword
Warning
hcodes
Hazard Classifications
Muta. 2
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Gamze Guney Eskiler et al.
Journal of biochemical and molecular toxicology, 33(8), e22338-e22338 (2019-04-14)
The aim of this study was to investigate the combined effects of usnic acid (UA) and Tamoxifen (Tam) or Enzalutamide (Enz) on hormone receptor-positive breast and prostate cancer (BC and PC), respectively. The antiproliferative and apoptotic effects of Tam or
Paulina Arévalo-Jaramillo et al.
Environmental science and pollution research international, 26(24), 24911-24921 (2019-06-28)
Toxicity refers to the potential of a substance such as a pesticide to cause damage to the structure or functions of an exposed organism. Pesticides can lead to harmful biological effects in exposed animals and their offspring over the medium
Dung Thuy Nguyen Pham et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 50(3), 791-805 (2019-06-30)
Biofilm formation is one of the resistance mechanisms of Pseudomonas aeruginosa against antimicrobial compounds. Biofilm formation also characterizes for the infection and pathogenesis of P. aeruginosa, along with production of various virulence factors. With recent development of nanotechnology, the present
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A8097-10ML | 04061833391204 |