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Merck
CN

B0301

生物素

meets USP testing specifications

别名:

D-生物素, Bios II, 维生素B7, 维生素H, 辅酶 R

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关于此项目

经验公式(希尔记法):
C10H16N2O3S
化学文摘社编号:
分子量:
244.31
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058011
UNSPSC Code:
12352201
EC Number:
200-399-3
MDL number:
Beilstein/REAXYS Number:
86838
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biological source

synthetic (organic)

Quality Level

agency

meets USP testing specifications

assay

97.5-102.0%

form

powder

color

white

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Application

<ul>
<li><strong>蛋白质生物素化研究:</strong>研究人员正在利用生物素来开发蛋白质中生物素化位点表征的先进策略,研究改善了对于生化研究和药物开发都很关键的蛋白质修饰技术的精确度(Zhu, 2024)。</li>
</ul>

Biochem/physiol Actions

对于氨基酸、能量代谢和脂肪酸合成有重要作用的必要维生素。它是四种哺乳类动物羧化酶中的辅基,促进二氧化碳的结合与输送。


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures


Tazu Aoki et al.
Neuron, 78(5), 881-894 (2013-05-21)
The encoding of long-term associative memories for learned behaviors is a fundamental brain function. Yet, how behavior is stably consolidated and retrieved in the vertebrate cortex is poorly understood. We trained zebrafish in aversive reinforcement learning and measured calcium signals
Stéphane Mann et al.
Biochimica et biophysica acta, 1814(11), 1459-1466 (2010-12-25)
The four last steps of biotin biosynthesis, starting from pimeloyl-CoA, are conserved among all the biotin-producing microorganisms. Two enzymes of this pathway, the 8-amino-7-oxononanoate synthase (AONS) and the 7,8-diaminopelargonic acid aminotransferase (DAPA AT) are dependent on pyridoxal-5'-phosphate (PLP). This review
John J Tukker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(16), 6809-6825 (2013-04-19)
Hippocampal CA3 area generates temporally structured network activity such as sharp waves and gamma and theta oscillations. Parvalbumin-expressing basket cells, making GABAergic synapses onto cell bodies and proximal dendrites of pyramidal cells, control pyramidal cell activity and participate in network



全球贸易项目编号

货号GTIN
901112-100MG04061833259498
B0301-25G04061833419670
B0301-500MG04061833419687
B0301-5G04061833419694