B2883
双苯并咪唑 H 33258
≥98% (HPLC)
别名:
BBIH, BXI-72, HOE 33258, Hoechst 33258, NSC334072, 烟酸己可碱 三盐酸盐, 甲嗪双苯咪酚 三盐酸盐
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关于此项目
经验公式（希尔记法）:
C25H24N6O · 3HCl
化学文摘社编号:
分子量:
533.88
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
245-690-6
Beilstein/REAXYS Number:
4088183
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
mp
280 °C
solubility
H2O: 10 mg/mL, water and ethanol: 10 mg/mL, phosphate buffer: precipitates
suitability
passes application test for fluorescence
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6
InChI
1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2
InChI key
OWRSPPSBNWJJAR-UHFFFAOYSA-N
Application
bisBenzimide H 33258已用于细胞中的核染色。
bisBenzimide H 33258可用于DNA、染色体和细胞核的染色。 bisBenzimide H 33258可用于荧光显微术或流式细胞术。
最大激发波长= 346nm
最大发射波长= 460nm
最大激发波长= 346nm
最大发射波长= 460nm
bisBenzimide H 33258可用于DNA、染色体和细胞核的染色。可用于荧光显微镜或流式细胞术。
Biochem/physiol Actions
bisBenzimide H 33258是一种有效的选择性Bcl-XL抑制剂。
bisBenzimide H 33258是一种有效的选择性Bcl-XL抑制剂。 bisBenzimide H 33258是一种膜可渗透的荧光DNA染色剂，具有低细胞毒性，可嵌入DNA的A-T区域。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
T Araki et al.
Histochemistry, 87(4), 331-338 (1987-01-01)
In an attempt to achieve accurate quantification of DNA levels in cell nuclei, we studied the influence of salt concentration on the fluorescence of cell nuclei complexed with Hoechst-33258 (Hoe) fluorochrome. The fluorescence of cell nuclei was compared with that
Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism.
Fu YS, et al.
Stem Cells, 24, 115-124 (2006)
Zev A Binder et al.
Cancer cell, 34(1), 163-177 (2018-07-11)
We explored the clinical and pathological impact of epidermal growth factor receptor (EGFR) extracellular domain missense mutations. Retrospective assessment of 260 de novo glioblastoma patients revealed a significant reduction in overall survival of patients having tumors with EGFR mutations at
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B2883-1G | 04061833427149 |
| B2883-100MG | 04061833427132 |
| B2883-25MG | 04061833427156 |
| B2883-500MG | 04061835345847 |