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BP460

烟酰胺

British Pharmacopoeia (BP) Reference Standard

别名:

吡啶-3-甲酰胺, 烟碱酰胺, 烟酰胺, 维生素 B3, 维生素 PP

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关于此项目

经验公式(希尔记法):
C6H6N2O
化学文摘社编号:
分子量:
122.12
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
383619
MDL number:
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grade

pharmaceutical primary standard

agency

BP

API family

nicotinamide

form

solid

manufacturer/tradename

BP

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

128-131 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide, a member of the family of water-soluble B vitamins, is generally produced from nicotinic acid (vitamin B3). It is often present in food products. It has been reported to have been effective in the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also shown to possess anti-inflammatory activity.

Application

Nicotinamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Vitamins B and C Injection
  • Nicorandil Tablets
  • Biochem/physiol Actions

    烟酰胺是维生素B3的酰胺衍生物,是PARP抑制剂

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.


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    pictograms

    Exclamation mark

    signalword

    Warning

    hcodes

    Hazard Classifications

    Eye Irrit. 2

    存储类别

    11 - Combustible Solids

    wgk

    WGK 1

    flash_point_f

    302.0 °F - closed cup

    flash_point_c

    150 °C - closed cup



    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Nicotinamide
    European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
    European pharmacopoeia, 14(4), 3145-3146 (2017)
    Evaluation of analytical tools and multivariate methods for quantification of co-former crystals in ibuprofen-nicotinamide co-crystals
    Soares FLF and Carneiro RL
    Journal of Pharmaceutical and Biomedical Analysis, 89, 166-175 (2014)
    Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceuticals and biological fluids after solid phase extraction
    Chatzimichalakis PF, et al.
    Journal of Separation Science, 27(14), 1181-1188 (2004)



    全球贸易项目编号

    货号GTIN
    BP46004061834303909