C4206
卡马西平 10,11-环氧化物
analytical standard
别名:
1a,10b-二氢-6H-二苯并(b,f)环氧乙烯并[d]氮呯-6-甲酰胺
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关于此项目
经验公式（希尔记法）:
C15H12N2O2
化学文摘社编号:
分子量:
252.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
analytical standard
Quality Level
assay
≥98% (HPLC)
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
−20°C
SMILES string
NC(=O)N1c2ccccc2C3OC3c4ccccc14
InChI
1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)
InChI key
ZRWWEEVEIOGMMT-UHFFFAOYSA-N
General description
卡马西平10,11-环氧化物是药物卡马西平的代谢产物。
Application
卡马西平10,11-环氧化物可用作测试材料，用于荧光HDAC活性测定法以定量组蛋白脱乙酰酶（HDAC）抑制。
有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
卡马西平的第一代谢产物
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Sigrid Mennickent et al.
Journal of separation science, 32(9), 1454-1458 (2009-03-31)
An instrumental planar chromatographic (HPTLC) method for quantification of carbamazepine in human serum was developed using liquid-liquid extraction with dichloromethane, fluorescence activation with perchloric acid 60%/ethanol/water (1:1:1, v/v) and fluorescence detection. Planar chromatographic separation was performed on precoated silica gel
Ana Fortuna et al.
Analytical and bioanalytical chemistry, 397(4), 1605-1615 (2010-04-20)
For the first time, a simple, selective and accurate high-performance liquid chromatography method with ultraviolet detection was developed and validated to quantify simultaneously three structurally related antiepileptic drugs; carbamazepine, oxcarbazepine, and the recently launched eslicarbazepine acetate and their main metabolites
Andreas S Beutler et al.
Life sciences, 76(26), 3107-3115 (2005-04-27)
Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and modulation of neurotransmitter levels. Whether it affects any component of the gene transcription machinery is unknown. Histone deacetylases (HDAC)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C4206-5MG | 04061833284568 |
| C4206-25MG | 04061833491836 |