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Merck
CN

E1100000

麦角甾醇

European Pharmacopoeia (EP) Reference Standard

别名:

(3β)-麦角-5,7,22-三烯甘油-3-醇, 3β-羟基-5,7,22-麦角三烯, 维生素原 D2

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关于此项目

经验公式(希尔记法):
C28H44O
化学文摘社编号:
分子量:
396.65
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2338604
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biological source

plant

grade

pharmaceutical primary standard

agency

EP

API family

ergosterol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

156-158 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C

InChI

1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1

InChI key

DNVPQKQSNYMLRS-APGDWVJJSA-N

General description

麦角固醇是在存在于真菌细胞膜和某些原生生物(如锥虫)中的维生素D2的生物前体。
本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

Application

麦角固醇可用作药物参考标准品,用于通过液相色谱测定药物制剂中的分析物。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

可能适用相应的销售限制。


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hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ergocalciferol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 54(12), 6604-6606 (201)
Analysis of ergosterol in single kernel and ground grain by gas chromatography- mass spectrometry
Dong Y, et al.
Journal of Agricultural and Food Chemistry, 54(12), 4121-4125 (2006)
M E da Silva Ferreira et al.
Medical mycology, 43 Suppl 1, S313-S319 (2005-08-23)
The continuous use of triazoles can result in the development of drug resistance. Azole-resistant clinical isolates, spontaneous and induced mutants of Aspergillus fumigatus have been documented. The azoles block the ergosterol biosynthesis pathway by inhibiting the enzyme 14-alpha-demethylase, product of



全球贸易项目编号

货号GTIN
E110000004061833793206