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G0325000

格列本脲

Name: 格列本脲
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

5-氯-N-[4-(环己基脲磺酰)苯乙基]-2-甲氧基苯甲酰胺, N-对[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰基-N′-环己基脲, 格列本脲

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关于此项目

经验公式（希尔记法）:

C₂₃H₂₈ClN₃O₅S

化学文摘社编号:

10238-21-8

分子量:

494.00

NACRES:

NA.24

PubChem Substance ID:

329799806

UNSPSC Code:

41116107

MDL number:

MFCD00056625

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属性

grade

pharmaceutical primary standard

API family

glybenclamide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3

InChI

1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)

InChI key

ZNNLBTZKUZBEKO-UHFFFAOYSA-N

Gene Information

human ... ABCC8(6833), KCNJ11(3767)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glybenclamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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hcodes

H413

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Novel approaches to the primary prevention of edema after ischemia.

Kevin N Sheth

Stroke, 44(6 Suppl 1), S136-S136 (2013-06-05)

Selective separation and enrichment of glibenclamide in health foods using surface molecularly imprinted polymers prepared via dendritic grafting of magnetic nanoparticles.

Ruoyu Wang et al.

Journal of separation science, 36(6), 1015-1021 (2013-02-19)

In this paper, the novel surface molecularly imprinted polymers based on dendritic-grafting magnetic nanoparticles were developed to enrich and separate glibenclamide in health foods. The density functional theory method was used to give theoretical directions to the synthesis of molecularly

Pilot study of intravenous glyburide in patients with a large ischemic stroke.

Kevin N Sheth et al.

Stroke, 45(1), 281-283 (2013-11-07)

Preclinical and retrospective clinical data indicate that glyburide, a selective inhibitor of sulfonylurea receptor 1-transient receptor potential melastatin 4, is effective in preventing edema and improving outcome after focal ischemia. We assessed the feasibility of recruiting and treating patients with

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全球贸易项目编号

货号	GTIN
G0325000	04061833623473