grade
pharmaceutical primary standard
API family
mannitol
manufacturer/tradename
EDQM
mp
167-170 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-KVTDHHQDSA-N
General description
Application
本欧洲药典参考标准仅用于欧洲药典中明确规定的用途。不保证适用于任何其他用途，用户请自行负责。本标准品不适用于人类或动物使用。
根据欧洲药典，用于配制下列给定溶液：
根据欧洲药典，用于配制下列给定溶液：
- 参考溶液 (b)，根据各论 1531，使用液相色谱法（通则 2.2.29）检测异麦芽酮糖醇中的相关物质
- 参考溶液 (a)，根据各论 0559，使用薄层色谱法（通则 2.2.27）和红外光谱法鉴别甘露醇，并使用液相色谱法（通则 2.2.29）测试和检测相关物质
- 参考溶液 (b)，根据各论 0435，使用薄层色谱法（通则 2.2.27）鉴定山梨醇
- 参考溶液 (b)，根据各论 1381，使用气相色谱法（通则 2.2.28）测试相关物质
Biochem/physiol Actions
一种糖醇类甜味剂。 用于甜味抑制研究。
Packaging
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
Other Notes
可能适用相应的销售限制。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Sorbitol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3865-3867 (2019)
Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M0200000 | 04061833992715 |