M8506
甲巯咪唑
analytical standard
别名:
1-甲基-2-巯基咪唑, MET, 1-甲基-2-咪唑硫醇, 2-巯基-1-甲基咪唑
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关于此项目
经验公式（希尔记法）:
C4H6N2S
化学文摘社编号:
分子量:
114.17
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39161002
UNSPSC Code:
41116107
EC Number:
200-482-4
MDL number:
Beilstein/REAXYS Number:
108646
grade
analytical standard
Quality Level
assay
≥99%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
144-147 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Information
human ... TPO(7173)
General description
甲基咪唑属于亚硫脲类化合物类别，用作治疗甲状腺功能亢进症的抗甲状腺药物。
Application
二丙酸倍氯米松分析标准品的使用方法如下：
- 银/石墨烯修饰碳糊电极（AgGCPE）电化学测定甲氧咪唑
- 以海藻酸钠保护的银纳米颗粒为 SERS 基质，开发基于表面增强拉曼散射（SERS）、估计丙基硫氧嘧啶和甲氧咪唑的的方法
- 基于金纳米颗粒（AuNPs）基底的表面增强拉曼光谱在超痕量极限下检测甲咪唑
- 高效液相色谱-串联质谱（HPLC-MS/MS）法定量分析人体血液样本中的甲巯咪唑
- 基于分子印迹聚合物（MIP）-笔状石墨电极（PGE）的传感器电化学测定片剂和人血清中的甲氧咪唑
Other Notes
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
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wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
target_organs
Endocrine system
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1A - Skin Sens. 1 - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
Francesco Isaia et al.
Journal of medicinal chemistry, 51(13), 4050-4053 (2008-06-06)
The antithyroid drug methimazole (MMI) reacts with molecular iodine to form, in a multistep process, 1-methylimidazole as final product. In this process, the charge transfer complex MMI-I 2 and the ionic disulfide [(C 4H 6N 2S-) 2] (2+) ( 1
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M8506-100G | 04061834063223 |
| M8506-25G | 04061834063230 |