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N0850000

尼莫地平

Name: 尼莫地平
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

1,4-二氢-2,6-二甲基-4-（3-硝基苯基）-3,5-吡啶二甲酸-2-甲氧基乙基1-甲基乙基酯, 1,4-二氢-2,6-二甲基-4-（间硝基苯基）-3,5-吡啶二甲酸异丙酯-2-甲氧基乙酯

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关于此项目

经验公式（希尔记法）:

C₂₁H₂₆N₂O₇

化学文摘社编号:

66085-59-4

分子量:

418.44

NACRES:

NA.24

PubChem Substance ID:

329818466

UNSPSC Code:

41116107

MDL number:

MFCD00153848

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属性

grade

pharmaceutical primary standard

API family

nimodipine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COCCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC(C)C

InChI

1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3

InChI key

UIAGMCDKSXEBJQ-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), NR3C2(4306)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nimodipine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bioanalytics of nimodipine--an overview of methods.

W Mück et al.

Die Pharmazie, 49(2-3), 130-139 (1994-02-01)

The analytical test procedures currently established for the determination of the dihydropyridine calcium antagonist nimodipine in biological fluids are presented. Method of choice which has been dominantly used in pharmacokinetic investigations and drug interaction studies is gas chromatography with electron-capture

Nimodipine in animal model experiments of focal cerebral ischemia: a systematic review.

J Horn et al.

Stroke, 32(10), 2433-2438 (2001-10-06)

Based on the results of animal experiments, clinical trials were performed with nimodipine, which did not demonstrate a beneficial effect on outcome after stroke. The aim of this study was to determine whether the evidence from animal experiments with nimodipine

Potential interactions between nimodipine and adrenal hormones.

R L Isaacson et al.

Annals of the New York Academy of Sciences, 765, 134-142 (1995-09-15)

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全球贸易项目编号

货号	GTIN
N0850000	04061833813195