N5535
烟酰胺
meets USP testing specifications
别名:
烟酰胺, 吡啶-3-甲酰胺, 烟碱酰胺, 维生素 B3, 维生素 PP
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关于此项目
经验公式（希尔记法）:
C6H6N2O
化学文摘社编号:
分子量:
122.12
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
202-713-4
Beilstein/REAXYS Number:
383619
MDL number:
biological source
synthetic (organic)
Quality Level
agency
USP/NF, meets USP testing specifications
assay
98.5-101.5% dry basis
form
crystals
color
white
mp
128-131 °C (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
NC(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
Gene Information
human ... PARP1(142), SIRT2(22933)
General description
烟酰胺，也称为3-吡啶甲酰胺，是水溶性维生素。在植物、动物性食品和化妆品中广泛存在。
Application
烟酰胺用于：
- 作为胰岛成熟培养基的组分
- 诱导胰岛素分泌细胞分化
- 比较其与孕酮的临床前疗效
Biochem/physiol Actions
烟酰胺是烟酰胺腺嘌呤二核苷酸（NAD+）的主要前体，而NAD+是三磷酸腺苷（ATP）产生过程中的重要辅酶。 烟酰胺缺乏与糙皮病有关。
烟酰胺是维生素B3的酰胺衍生物，是PARP抑制剂
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Stimulatory Role of Glycated Fetal Bovine Serum Along with Iron on In Vitro Production of Insulin by Differentiated Mouse Embryonic Stem Cells
Nishigaki I, et al.
Journal of Health Science, 57(4), 356-361 (2011)
A comparison of the effects of nicotinamide and progesterone on functional recovery of cognitive behavior following cortical contusion injury in the rat
Peterson TC, et al.
Journal of Neurotrauma, 29(18), 2823-2830 (2012)
Role of nicotinamide in DNA damage, mutagenesis, and DNA repair
Surjana D, et al.
Journal of Nucleic Acids, 2010 (2010)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N5535-100G | 04061835547067 |