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N6522

β-烟酰胺腺嘌呤二核苷酸水合物

Name: β-烟酰胺腺嘌呤二核苷酸 水合物
Brand: SIAL

≥98%, BioUltra, from yeast

别名:

β-DPN, β-NAD, DPN, NAD, 二磷酸吡啶核苷酸, 辅酶, 辅酶 1, 辅酶 A

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关于此项目

经验公式（希尔记法）:

C₂₁H₂₇N₇O₁₄P₂ · xH₂O

化学文摘社编号:

53-84-9

分子量:

663.43 (anhydrous basis)

PubChem Substance ID:

24897783

eCl@ss:

39200202

UNSPSC Code:

41106305

NACRES:

NA.55

EC Number:

200-184-4

MDL number:

MFCD00036253

Form:

powder

Assay:

≥98%

Solubility:

H₂O: 0.1 M, clear, colorless to faintly yellow

Biological source:

yeast

Color:

white to off-white

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属性

biological source

yeast

Quality Level

200

product line

BioUltra

assay

≥98%

form

powder

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤0.1% Insoluble matter

color

white to off-white

solubility

H₂O: 0.1 M, clear, colorless to faintly yellow

anion traces

chloride (Cl^-): ≤0.2%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.001%, Fe: ≤0.001%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

greener alternative category

DfS-Developed

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

Gene Information

human ... ESR1(2099), ESR2(2100)

说明

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application

电化学传感器开发：在基于碳纳米材料的电化学传感器和生物传感器的开发中，研究人员采用了β-烟酰胺腺嘌呤二核苷酸水化物。这些设备是为了药物和生物化合物的灵敏检测而设计，彰显了其改善生物化学分析的灵敏度和特异性的关键作用（Adhikari et al., 2015）。

Biochem/physiol Actions

电子受体

Packaging

根据固体质量包装。

Other Notes

本品是普通型 NAD。

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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

醇脱氢酶（EC 1.1.1.1）的酶学测定

在测定醇脱氢酶活性时，该测定使用β-烟酰胺腺嘌呤二核苷酸磷酸和在340nm处的连续分光光度法进行测定。

Enzymatic Assay of Alcohol Dehydrogenase (EC 1.1.1.1)

To measure alcohol dehydrogenase activity, this assay uses β-nicotinamide adenine dinucleotide phosphate and a continuous spectrophotometric rate determination at 340 nm.

Respiration control of multicellularity in Bacillus subtilis by a complex of the cytochrome chain with a membrane-embedded histidine kinase.

Ilana Kolodkin-Gal et al.

Genes & development, 27(8), 887-899 (2013-04-20)

Bacillus subtilis forms organized multicellular communities known as biofilms wherein the individual cells are held together by a self-produced extracellular matrix. The environmental signals that promote matrix synthesis remain largely unknown. We discovered that one such signal is impaired respiration.

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

Brian J North et al.

The EMBO journal, 33(13), 1438-1453 (2014-05-16)

Mice overexpressing the mitotic checkpoint kinase gene BubR1 live longer, whereas mice hypomorphic for BubR1 (BubR1(H/H)) live shorter and show signs of accelerated aging. As wild-type mice age, BubR1 levels decline in many tissues, a process that is proposed to

Benzophenones from an endophytic fungus, Graphiopsis chlorocephala, from Paeonia lactiflora cultivated in the presence of an NAD+-dependent HDAC inhibitor.

Teigo Asai et al.

Organic letters, 15(8), 2058-2061 (2013-04-13)

Graphiopsis chlorocephala was separated from the surface-sterilized healthy leaves of Paeonia lactiflora (Paeoniaceae) and cultivated with nicotinamide (an NAD(+)-dependent HDAC inhibitor). The culture conditions significantly enhanced secondary metabolite production in the fungus and led to the isolation of a structurally

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