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O5015

盐酸奥昔布宁

Name: 盐酸奥昔布宁
Brand: SIAL

meets EP, USP testing specifications

别名:

α-苯基环己烷乙醇酸 4-(二乙基氨基)-2-丁炔酯盐酸盐

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关于此项目

经验公式（希尔记法）:

C₂₂H₃₁NO₃ · HCl

化学文摘社编号:

1508-65-2

分子量:

393.95

NACRES:

NA.21

PubChem Substance ID:

24898008

UNSPSC Code:

12161900

EC Number:

216-139-7

MDL number:

MFCD00072150

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属性

Quality Level

200

agency

USP/NF, meets EP testing specifications, meets USP testing specifications

form

solid

application(s)

pharmaceutical (small molecule)

storage temp.

room temp

SMILES string

Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H

InChI key

SWIJYDAEGSIQPZ-UHFFFAOYSA-N

Gene Information

human ... CHRM2(1129), CHRM3(1131)

说明

Biochem/physiol Actions

毒蕈碱型乙酰胆碱受体拮抗剂。

毒蕈碱型乙酰胆碱受体拮抗剂；可能通过下调生长促进基因，抑制膀胱平滑肌细胞的增殖。

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effects of mirabegron, a novel β3-adrenoceptor agonist, on primary bladder afferent activity and bladder microcontractions in rats compared with the effects of oxybutynin.

Naoki Aizawa et al.

European urology, 62(6), 1165-1173 (2012-09-18)

Mirabegron is the first β3-adrenoceptor agonist that is clinically effective for overactive bladder. The effects of mirabegron on primary bladder mechanosensitive single-unit afferent activities (SAAs) and bladder microcontractions were evaluated and compared with the effects of oxybutynin. Female Sprague-Dawley rats

Clinical effectiveness of early treatment with hyperbaric oxygen therapy for severe late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation in pediatric patients.

Daniele Zama et al.

Pediatric transplantation, 17(1), 86-91 (2012-12-13)

HC is a possible cause of morbidity and extended hospitalization after HSCT. Recent studies have reported the efficiency of HOT in adult patients who underwent allogeneic HSCT, but data in children are scarce. We report our single center experience with

P Tauzin-Fin et al.

Annales francaises d'anesthesie et de reanimation, 31(7-8), 605-608 (2012-07-04)

Catheter-related bladder discomfort (CRBD) is an unrecognized clinical event. Symptoms of CRBD secondary to an indwelling urinary catheter mimic those of an overactive bladder, i.e. urinary frequency and urgency with or without urge incontinence. Stimulation of muscarinic receptors located in

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全球贸易项目编号

货号	GTIN
O5015-500MG	04061833435571
O5015-1G	04061826695128
O5015-5G	04061833429235