Quality Level
biological source
Porcine (tallow), bovine (tallow)
description
non-ionic
form
viscous liquid
mol wt
micellar avg mol wt 79,000, average mol wt 1310
composition
Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)
aggregation number
60
CMC
0.012 mM (20-25°C)
viscosity
400-620 mPa.s
transition temp
cloud point 65 °C
solubility
water: soluble, clear to slightly hazy, colorless to yellow
density
1.064 g/cm3
HLB
15
application(s)
cell analysis
SMILES string
CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
InChI
1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
InChI key
RGPBUVUVZKQNHD-MDZDMXLPSA-N
General description
Tween® 80（吐温80）是一种非离子去污剂和表面活性剂，属于山梨聚糖油酸酯。它是一种多功能化合物，常用于各种生物学应用，包括细胞裂解、核分离和细胞分级分离。此外，吐温80可用于稳定蛋白质，并有助于蛋白质膜研究。其功效来源于聚山梨醇酯基团，该基团的特点是山梨醇和山梨聚糖油酸酯与聚乙二醇链的结合。这些结构特性造就了吐温80的乳化能力和广泛应用。
Application
TWEEN® 80已用于小鼠和大鼠中特异性注射中的药物载体溶液。它已用于测定细菌细胞中酯酶的活性。
用于从哺乳动物细胞系中选择性提取蛋白质、分离细胞核的非离子型去垢剂。
Biochem/physiol Actions
TWEEN® 80是一种可助力于蛋白质稳定和蛋白质膜研究的聚山梨醇酯表面活性剂。它常用于进行膜蛋白的提取以及从细胞中进行细胞核分离。
Features and Benefits
- 优良的润湿和分散剂
- 适用于细胞生物学和生物化学研究的多功能表面活性剂
Legal Information
TWEEN is a registered trademark of Croda International PLC
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存储类别
10 - Combustible liquids
ppe
Eyeshields, Gloves
flash_point_f
>482.0 °F - Cleveland open cup
flash_point_c
> 250 °C - Cleveland open cup
Pathogenic factors of Pseudomonas cepacia isolates from patients with cystic fibrosis.
Gessner AR and Mortensen JE
Journal of Medical Microbiology, 33, 115-115 (1990)
Handbook of Biochemistry and Molecular Biology (2010)
Thibaut Frachon et al.
Langmuir : the ACS journal of surfaces and colloids, 32(49), 13009-13019 (2016-12-14)
Therapeutic proteins are privileged in drug development because of their exquisite specificity, which is due to their three-dimensional conformation in solution. During their manufacture, storage, and delivery, interactions with material surfaces and air interfaces are known to affect their stability.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P1754-10ML-KC | 04061838088253 |
| P1754-25ML | 04061837602399 |
| P1754-500ML | 04061837602405 |
| P1754-1GA | 04061837602375 |
| P1754-1L | 04061837602382 |