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P8721

青霉素G 钾盐

Name: 青霉素G 钾盐
Brand: SIAL

别名:

苄青霉素钾盐

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₇KN₂O₄S

化学文摘社编号:

113-98-4

分子量:

372.48

NACRES:

NA.21

PubChem Substance ID:

24898970

eCl@ss:

34010400

UNSPSC Code:

51283405

EC Number:

204-038-0

MDL number:

MFCD00036193

Beilstein/REAXYS Number:

3832841

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属性

form

crystalline powder

Quality Level

200

potency

1440-1680 units per mg

antibiotic activity spectrum

Gram-positive bacteria

application(s)

pharmaceutical (small molecule)

mode of action

cell wall synthesis | interferes

SMILES string

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

说明

General description

Chemical structure: β-lactam

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Biochem/physiol Actions

作用机制：青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联，从而抑制细胞壁合成。

抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

Packaging

10mu,25mu,100mu

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

Disclaimer

溶液应过滤杀菌，在 2-8°C 下最长可储存一周，在 -20°C 下可长期储存。溶液在 37°C 下可稳定 3 天。

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pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P280 - P302 + P352

Hazard Classifications

Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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PspA family distribution, antimicrobial resistance and serotype of Streptococcus pneumoniae isolated from upper respiratory tract infections in Japan.

Muneki Hotomi et al.

PloS one, 8(3), e58124-e58124 (2013-03-14)

The protection against pneumococcal infections provided by currently available pneumococcal polysaccharide conjugate vaccines are restricted to the limited number of the serotypes included in the vaccine. In the present study, we evaluated the distribution of the pneumococcal capsular type and

[Congenit syphilis in a baby].

Tina Lund Leunbach et al.

Ugeskrift for laeger, 175(11), 742-743 (2013-03-14)

A pregnant Caucasian woman with newly diagnosed syphilis in the secondary stage was hospitalized for observation while being treated with penicillin. After one dose of penicillin the foetus was delivered by a caesarean section at gestational age 28 weeks +

[A study on early-onset group "B" streptococcal neonatal infection].

R Vacheva et al.

Akusherstvo i ginekologiia, 51(6), 10-21 (2013-02-09)

The results achieved with 80% reduction in the incidence of early-onset neonatal group B streptococcal (GBS) sepsis following the implementation of the preliminary (1996, 2002) and subsequently the revised (2010) guidelines for intrapartum antibiotic prophylaxis imposed the discussion on a

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全球贸易项目编号

货号	GTIN
P8721-100MU	04061834401698
P8721-10MU	04061834401704
P8721-25MU	04061834407379