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PHR1273

苹果酸

Name: 苹果酸
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

DL-苹果酸, (±)-2-羟基琥珀酸, DL-羟基丁二酸

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关于此项目

线性分子式:

HO₂CCH₂CH(OH)CO₂H

化学文摘社编号:

6915-15-7

分子量:

134.09

NACRES:

NA.24

E Number:

E296

PubChem Substance ID:

329823269

UNSPSC Code:

41116107

EC Number:

230-022-8

MDL number:

MFCD00064212

Beilstein/REAXYS Number:

1723539

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属性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000143, traceable to USP 1374601

vapor density

4.6 (vs air)

vapor pressure

<0.1 mmHg ( 20 °C)

API family

malic acid

CofA

current certificate can be downloaded

autoignition temp.

644 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

131-133 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(CC(O)=O)C(O)=O

InChI

1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)

InChI key

BJEPYKJPYRNKOW-UHFFFAOYSA-N

说明

General description

苹果酸是一种天然存在的酸化剂和弱酸性食品添加剂，存在于大多数水果和蔬菜中。它被广泛用于增强风味，调节碱性产品的pH值，控制细菌的生长。

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Application

这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

本认证参考材料是根据国际标准化组织指南 17034 和国际标准化组织/国际电工委员会17025 生产和认证的。所有关于客户关系管理的信息都可以在分析证书上找到。

要查看该材料的分析证书示例，请在下面的栏位中输入LRAA0009。这只是一个示例证书，可能不是您收到的批次。

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pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

397.4 °F

flash_point_c

203 °C

分析证书(COA)

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实验方案

HPLC Analysis of Organic Acids in Wine/Beer on TSKgel^®

Science Slam panel: Leading gene therapy developers discuss commercialization challenges and the importance of robust process development plans.

dl-Malic acid as a component of α-hydroxy acids: effect on 2,4-dinitrochlorobenzene-induced inflammation in atopic dermatitis-like skin lesions in vitro and in vivo.

Bina Lee et al.

Immunopharmacology and immunotoxicology, 41(6), 614-621 (2019-10-28)

Background: dl-Malic acid (dl-M) is used widely in cosmetic formulations as a pH-adjuster or as a preservative. dl-M is used as an exfoliator in the form of α-hydroxy acids. However, the role of dl-M in skin diseases (including atopic dermatitis

Fundamentals of Food Biotechnology (2014)

Reassessment of the transhydrogenase/malate shunt pathway in Clostridium thermocellum ATCC 27405 through kinetic characterization of malic enzyme and malate dehydrogenase.

M Taillefer et al.

Applied and environmental microbiology, 81(7), 2423-2432 (2015-01-27)

Clostridium thermocellum produces ethanol as one of its major end products from direct fermentation of cellulosic biomass. Therefore, it is viewed as an attractive model for the production of biofuels via consolidated bioprocessing. However, a better understanding of the metabolic

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全球贸易项目编号

货号	GTIN
PHR1273-1G	04061834415596