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Merck
CN

PHR1343

磺胺嘧啶

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

磺胺嘧啶, N-2-嘧啶基-4-氨基苯磺酰胺, N1-(嘧啶-2-基)磺胺

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关于此项目

经验公式(希尔记法):
C10H10N4O2S
化学文摘社编号:
分子量:
250.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-685-8
Beilstein/REAXYS Number:
6733588
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. S1800000, traceable to USP 1625009

API family

sulfadiazine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

253 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

InChI

1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

InChI key

SEEPANYCNGTZFQ-UHFFFAOYSA-N

General description

Sulfadiazine is a bacteriostatic drug, that belongs to the class of medication referred as sulfonamide antibiotics. It is generally used in the treatment of cerebral meningitis, pneumonia, staphylococcal and streptococcal sepsis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Sulfadiazine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3953 in the slot below. This is an example certificate only and may not be the lot that you receive.


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 2



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Sulfadiazine
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 4106-4106 (2018)
Sulfonamide antibiotics
Connor EE
Primary Care Update for OB/GYNS, 5(1), 32-35 (1998)
Simultaneous determination of enrofloxacin, silver sulfadiazine, hydrocortisone acetate, hydrocortisone sodium succinate, and preservative excipients in pharmaceutical preparations using HPLC-DAD method
Rosa AM, et al.
Chromatographia, 80(11), 1641-1649 (2017)



全球贸易项目编号

货号GTIN
PHR1343-500MG04061835233748