grade
anhydrous
Quality Level
product line
Redi-Dri™
assay
≥99.0%
quality
free-flowing
pKa (25 °C)
9.5
mp
82-84 °C (lit.)
SMILES string
NCCO.[H]Cl
InChI
1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChI key
PMUNIMVZCACZBB-UHFFFAOYSA-N
General description
Ethanolamine hydrochloride, a versatile compound in biochemistry and molecular biology, plays a pivotal role in diverse research areas. Primarily, it functions as a buffering agent, ensuring a stable pH environment crucial for enzymatic reactions, protein solubilization, and other biological processes. Its significance extends to membrane protein studies, aiding in the extraction of these proteins from cell membranes. It also finds utility in cell culture and as a reagent for biological sample preparation, simplifying nucleic acid and protein isolation, as well as facilitating the detection of proteins by western blotting and immunohistochemistry. This compound′s wide-ranging applications make it indispensable in biochemical research, contributing to various experimental procedures and advancing our understanding in fields such as molecular biology, immunology, and cellular biology.
Application
Ethanolamine hydrochloride has been used:
- in overnight incubation of the tips to attach primary amine groups at the tip surface
- in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors
- to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process
Biochem/physiol Actions
Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically. It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane. Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia. Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.
Features and Benefits
- Suitable for molecular biology
- Redi-Dri packaging controls moisture for hygroscopic chemicals that commonly clump
- Powder remains free-flowing and easy to use
- Safer to handle and weigh out for routine use in the lab
- Eliminates clumps, maintaining product moisture, quality, and product specifications
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
商品
Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.
K C Andree et al.
Lab on a chip, 19(6), 1006-1012 (2019-02-15)
The load of circulating tumor cells (CTC) is related to poor outcomes in cancer patients. A sufficient number of these cells would enable a full characterization of the cancer. An approach to probe larger blood volumes, allowing for the detection
Foodborne Diseases: New Insights for the Healthcare Professional, 14-14 (2012)
Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth
Mendoza N, et al.
Cancer Research, 63(5), 1020-1024 (2003)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RDD028-1KG | 04065265076296 |
| RDD028-500G | 04061842154678 |
| RDD028-100G | 04061841846796 |