T0891
甲苯磺丁脲
analytical standard
别名:
1-丁基-3-（4-甲基苯磺酰基）脲, N-[(丁基氨基)羰基]-4-甲基苯磺酰胺
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关于此项目
经验公式（希尔记法）:
C12H18N2O3S
化学文摘社编号:
分子量:
270.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-594-3
Beilstein/REAXYS Number:
1984428
MDL number:
biological source
synthetic (organic)
Quality Level
grade
analytical standard
assay
97.0-103.0%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
solubility
ethanol: 50 mg/mL, clear, colorless
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1
InChI
1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
InChI key
JLRGJRBPOGGCBT-UHFFFAOYSA-N
Gene Information
human ... ABCC8(6833), ALB(213), CYP1A2(1544), CYP2C9(1559), EPHX2(2053), KCNJ1(3758), KCNJ11(3767)
mouse ... Ephx2(13850)
Application
有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。
Biochem/physiol Actions
抗糖尿病制剂。由CYP2C9（甲苯磺丁脲羟化酶）所代谢。
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Kevin S C Hamming et al.
Diabetes, 59(7), 1686-1693 (2010-04-24)
The sodium-calcium exchanger isoform 1 (NCX1) regulates cytoplasmic calcium (Ca(2+)(c)) required for insulin secretion in beta-cells. NCX1 is alternatively spliced, resulting in the expression of splice variants in different tissues such as NCX1.3 and -1.7 in beta-cells. As pharmacological inhibitors
Ioannis Eleftherianos et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(29), 12024-12029 (2011-07-02)
The effects of the cellular environment on innate immunity remain poorly characterized. Here, we show that in Drosophila ATP-sensitive potassium channels (K(ATP)) mediate resistance to a cardiotropic RNA virus, Flock House virus (FHV). FHV viral load in the heart rapidly
Ruurdtje Hoekstra et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(3), 562-567 (2012-12-15)
The human liver cell line HepaRG has been recognized as a promising source for in vitro testing of metabolism and toxicity of compounds. However, currently the hepatic differentiation of these cells relies on exposure to dimethylsulfoxide (DMSO), which, as a
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T0891-100G | 04061837335983 |
| T0891-25G | 04061837336027 |
| T0891-500G | 04061837336034 |