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T1700000

甲苯磺丁脲

Name: 甲苯磺丁脲
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

1-丁基-3-（4-甲基苯磺酰基）脲, N-[(丁基氨基)羰基]-4-甲基苯磺酰胺

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₈N₂O₃S

化学文摘社编号:

64-77-7

分子量:

270.35

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329826684

MDL number:

MFCD00027169

Beilstein/REAXYS Number:

1984428

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属性

grade

pharmaceutical primary standard

API family

tolbutamide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)

InChI key

JLRGJRBPOGGCBT-UHFFFAOYSA-N

Gene Information

human ... ABCC8(6833), KCNJ11(3767)

说明

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

Application

甲苯磺丁脲EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Biochem/physiol Actions

抗糖尿病制剂。由CYP2C9（甲苯磺丁脲羟化酶）所代谢。

Packaging

本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。

Other Notes

可能适用相应的销售限制。

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Paulette B Goforth et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(34), 11405-11415 (2014-08-22)

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Analysis of free drug fractions by ultrafast affinity extraction: interactions of sulfonylurea drugs with normal or glycated human serum albumin.

Xiwei Zheng et al.

Journal of chromatography. A, 1371, 82-89 (2014-12-03)

Ultrafast affinity extraction and a multi-dimensional affinity system were developed for measuring free drug fractions at therapeutic levels. This approach was used to compare the free fractions and global affinity constants of several sulfonylurea drugs in the presence of normal

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全球贸易项目编号

货号	GTIN
T1700000	04061837338069