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U0020000

辅酶Q10

Name: 辅酶Q10
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

辅酶 Q₁₀, Q-10, 辅酶Q10, 辅酶Q50

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关于此项目

经验公式（希尔记法）:

C₅₉H₉₀O₄

化学文摘社编号:

303-98-0

分子量:

863.34

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329827586

MDL number:

MFCD00042919

Beilstein/REAXYS Number:

1900141

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属性

biological source

fermentation/recombinant (yeast)

grade

pharmaceutical primary standard

agency

API family

ubidecarenone

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

49 °C

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O

InChI

1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

InChI key

ACTIUHUUMQJHFO-UPTCCGCDSA-N

说明

General description

Ubidecarenone, referred to as coenzyme Q, is abundantly available in human cells, with major proportions being present in vital body organs such as heart and kidneys. It plays an important role in cell metabolism owing to its significant contribution to the electron transport pathway. It is a strong antioxidant and acts as an essential enzyme catalyst in mitochondrial oxidative phosphorylation.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ubidecarenone may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and (2015)

Coenzyme Q10 inhibits the activation of pancreatic stellate cells through PI3K/AKT/mTOR signaling pathway

Xue R, et al.

Oncotarget, 8(54), 92300-92300 (2017)

Ubidecarenone

European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare

European pharmacopoeia, 8(54), 3875-3876 (2016)

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货号	GTIN
U0020000	04061833794357