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Y0000786

迷迭香酸

Name: 迷迭香酸
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(R)-O-(3,4-二羟基肉桂酰)-3-(3,4-二羟苯基)乳酸, 3,4-二羟基肉桂酸 ( R )-1-羧基-2-（3,4-二羟基苯基）乙酯

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关于此项目

经验公式（希尔记法）:

C₁₈H₁₆O₈

化学文摘社编号:

20283-92-5

分子量:

360.31

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329831150

MDL number:

MFCD00017740

Beilstein/REAXYS Number:

2227587

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属性

grade

pharmaceutical primary standard

API family

rosmarinic acid

manufacturer/tradename

EDQM

mp

171-175 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2

InChI

1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1

InChI key

DOUMFZQKYFQNTF-WUTVXBCWSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rosmarinic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Rosmarinic acid has shown to contain antioxidant and anti-inflammatory activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kidney disease treatment, cardioprotection and cancer chemoprevention.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Radiosensitizing effect of rosmarinic acid in metastatic melanoma B16F10 cells.

Miguel Alcaraz et al.

Anticancer research, 34(4), 1913-1921 (2014-04-03)

Rosmarinic acid is an ester of caffeic acid with interesting biological activities including antioxidant effects and scavenging of oxygen-free radicals. To determine the potentially paradoxical effect of rosmarinic acid, typically being radioprotective when applied to non-tumorous cells, yet conversely displaying

Rosmarinic acid and its derivatives: biotechnology and applications.

Victor P Bulgakov et al.

Critical reviews in biotechnology, 32(3), 203-217 (2011-08-16)

Rosmarinic acid (RA) is one of the first secondary metabolites produced in plant cell cultures in extremely high yields, up to 19% of the cell dry weight. More complex derivatives of RA, such as rabdosiin and lithospermic acid B, later

Evolution of rosmarinic acid biosynthesis.

Maike Petersen et al.

Phytochemistry, 70(15-16), 1663-1679 (2009-06-30)

Rosmarinic acid and chlorogenic acid are caffeic acid esters widely found in the plant kingdom and presumably accumulated as defense compounds. In a survey, more than 240 plant species have been screened for the presence of rosmarinic and chlorogenic acids.

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全球贸易项目编号

货号	GTIN
Y0000786	04061837583827