N,N-二甲基甲酰胺

N, N-二甲基甲酰胺（DMF）是一种有机化合物，在有机合成中常用作试剂和溶剂。它在各种反应中起着多重作用，如甲酰化剂、脱水剂、还原剂以及催化剂。

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DMF 可用作：     

• 有机金属化合物的甲酰化剂。
• 反应物，通过与氯化氧磷的反应制备 Vilsmeier 试剂。
• 试剂，在叔丁醇钾环境下进行芳酰氯的胺化。     
• 金属盐的还原剂，用于制备金属胶体。
• 催化剂，用于无保护碳水化合物的区域选择性硅基化。

DMF 还可用于以下用途：     

• DMF-光气催化体系用于从乙醇制备烷基卤化物。      
• DMF-POCl₃ 用于将无环和环烯化酮转化为 β-氯-α, β-不饱和醛。
• DMF-POCl₃ 用于从酰基苯胺合成喹啉-3-羧基。      
• DMF-SOCl₂ 混合物用于将氧脱水成腈。      
• DMF-Ag₂O 将 α-溴丙酰胺转化为恶唑烷酮。
• DMF 在许多要求高溶解力的化学反应中经常用作溶剂。

多种疏水性有机化合物的溶剂。