Quality Level
product line
ReagentPlus®
assay
≥99.90%
form
liquid
contains
50 ppm BHT as inhibitor
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
dilution
(for general lab use)
impurities
≤50 ppm H2O2
bp
106 °C/760 mmHg
mp
-140 °C
density
0.86 g/mL at 25 °C
greener alternative category
SMILES string
COC1CCCC1
InChI
1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3
InChI key
SKTCDJAMAYNROS-UHFFFAOYSA-N
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Cyclopentyl methyl ether (CPME) is a greener alternative solvent to many aprotic ether solvents such as tetrahydrofuran (THF), 2-methyl tetrahydrofuran (2-MeTHF), dioxane (carcinogenic), tert-Butyl methyl ether (MTBE), and 1,2-dimethoxyethane (DME) and thus has been enhanced for "Safer Solvents and Auxiliaries". Click here for more information.
Application
CPME is a greener alternative solvent and may be used is a broad range of applications such as:
Organic synthesis reactions containing the following reagents and conditions:
- Alkali agents
- Lewis’s acid-mediated reactions
- Organometallic
- Reduction and Oxidation
- Transition metal catalysts
- Azeotropic water removal
Extraction of compounds
Polymer synthesis
Crystallization
Surface coatings
Features and Benefits
- Synthetic-based sustainable and safer alternative
- Reduces the number of steps required for production
- Reduces the amount of water that is required for washing
- Eliminates the need for co-solvents for product recovery
It has many properties which make it a safer and greener alternative:
- Low peroxide formation
- High boiling point
- Clean organic-water phase separation
- Reduced energy to recover
Other Notes
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
存储类别
3 - Flammable liquids
flash_point_f
30.2 °F - closed cup - (External MSDS)
flash_point_c
-1 °C - closed cup - (External MSDS)
法规信息
危险化学品
此项目有
Replacement of dichloromethane within chromatographic purification: a guide to alternative solvents
MacMillan, D.S.; et al.
Green Chemistry (2012)
Cyclopentyl Methyl Ether as a New and Alternative Process Solvent
Watanabe, K.; Yamagiwa, N.; Torisawa, Y.
Organic Process Research & Development, 11 (2007)
Rikako Takahiro et al.
Biological & pharmaceutical bulletin, 38(1), 58-65 (2015-03-07)
The aim of this study was to characterize the kinetics of metabolite formation of the phosphodiesterase type-5 (PDE5) inhibitors sildenafil and tadalafil by CYP3A4, CYP3A5, and CYP3A7 isoforms. The formations of N-desmethyl sildenafil and desmethylene tadalafil were examined using CYP3A
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 675989-200L | 04061838152602 |
| 675989-4X4L | 04061832748016 |
| 675989-6X1L | 04061837225017 |
| 675989-18L | 04061837715372 |
| 675989-1L | 04061832747996 |
| 675989-4L | 04061832748009 |
| 675989-500ML | 04061837225000 |

