08658
8-氨基萘-1,3,6-三磺酸 二钠盐
BioReagent, suitable for fluorescence, ≥90% (CE)
别名:
8-氨基-1,3,6-萘三磺酸二钠, ANTS
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关于此项目
经验公式（希尔记法）:
C10H7NNa2O9S3
化学文摘社编号:
分子量:
427.34
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
226-431-6
MDL number:
Beilstein/REAXYS Number:
3854839
product line
BioReagent
Quality Level
assay
≥90% (CE)
impurities
~8% water
solubility
15% acetic acid: soluble, H2O: soluble
fluorescence
λex 356 nm; λem 512 nm in 0.1 M phosphate pH 7.0
suitability
suitable for fluorescence
InChI
1S/C10H9NO9S3.2Na/c11-8-3-6(21(12,13)14)1-5-2-7(22(15,16)17)4-9(10(5)8)23(18,19)20;;/h1-4H,11H2,(H,12,13,14)(H,15,16,17)(H,18,19,20);;/q;2*+1/p-2
InChI key
KHJANRFXWPPWEL-UHFFFAOYSA-L
Application
用于寡糖测序的糖类和糖蛋白荧光标记。
糖和糖蛋白的荧光标记，用于寡糖测序以及膜通透性和脂质体裂解的研究。
该分子试剂是一种聚阴离子染料，通常会与阳离子猝灭剂DPX（X1525）结合用于膜融合或通透性测定，包括补体介导的免疫裂解。ANTS的荧光已证实可被铊和铯离子有效淬灭。可用作神经元示踪剂。ANTS在水中具有相对较高的斯托克斯位移，这足以将其发射的光与生物样品的大多数自发荧光区分开。 D2O可将ANTS的荧光量子产率提高四倍，而这已被证明可用于测定红细胞鬼影和肾脏收集管中的透水性。碳水化合物的还原末端可与ANTS分子的伯氨基发生反应形成席夫碱，其随后可通过氰基硼氢化钠被还原为仲胺。该还原性胺化反应是酸催化的，因此反应溶液的pH值可通过ANTS改变碳水化合物的动力学和衍生化程度。需要特别注意的是，该反应能够在中性pH下进行，而这对于寡糖中对酸水解敏感的唾液酸键的完整性是有利的。用ANTS对碳水化合物进行这样的标记使得通过毛细管电泳对复杂的混合物进行分离成为可能。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时，它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因，它们在细胞表面的表现通常被称为“糖”。
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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